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TOP1MT antibody (C-Term)

TOP1MT Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774452
  • Target See all TOP1MT Antibodies
    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
    Binding Specificity
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
    Host
    • 19
    • 12
    Rabbit
    Clonality
    • 17
    • 14
    Polyclonal
    Conjugate
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TOP1MT antibody is un-conjugated
    Application
    • 11
    • 11
    • 10
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    KKRRLLEKLQ EQLAQLSVQA TDKEENKQVA LGTSKLNYLD PRISIAWCKR
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Yeast: 79%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against TOP1MT. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human TOP1MT
    Top Product
    Discover our top product TOP1MT Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 601 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
    Alternative Name
    TOP1MT (TOP1MT Products)
    Synonyms
    2900052H09Rik antibody, TOP1 antibody, topoisomerase (DNA) I, mitochondrial antibody, DNA topoisomerase 1, mitochondrial antibody, DNA topoisomerase I mitochondrial antibody, TOP1MT antibody, Top1mt antibody
    Background
    This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Alias Symbols: -
    Protein Interaction Partner: SUMO1, FSHR, UBC,
    Protein Size: 601
    Molecular Weight
    70 kDa
    Gene ID
    116447
    NCBI Accession
    NM_052963, NP_443195
    UniProt
    Q969P6
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