TTDN1 antibody (Middle Region)

Catalog No. ABIN2774466

Product Details anti-TTDN1 Antibody

Target: TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))

Binding Specificity: Middle Region

Reactivity: Human, Rabbit, Rat, Cow, Dog, Guinea Pig, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTDN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGGYPGSYSR SPAGSQQQFG YSPGQQQTHP QGSPRTSTPF GSGRVREKRM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MPLKIP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MPLKIP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 179 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTDN1

Target: TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))

Alternative Name: MPLKIP (MPLKIP Products)

Synonyms: ABHS antibody, C7orf11 antibody, ORF20 antibody, 2810021B07Rik antibody, C330007M08Rik antibody, Ttdn1 antibody, M-phase specific PLK1 interacting protein antibody, M-phase specific PLK1 intereacting protein antibody, MPLKIP antibody, Mplkip antibody

Background: The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.
Alias Symbols: ABHS, C7orf11, ORF20
Protein Interaction Partner: MRPL53, SARNP, SUGP1, CDV3, RBM27, SBDS, SF3B4, PPIF, SCAMP3, SF1, THY1, SCP2, NDUFA7, SERPINH1,
Protein Size: 179

Molecular Weight: 20 kDa

Gene ID: 136647

NCBI Accession: NM_138701, NP_619646

UniProt: Q8TAP9