PJA2 antibody (N-Term)

Catalog No. ABIN2774721

Product Details anti-PJA2 Antibody

Target: PJA2 (Praja Ring Finger 2 (PJA2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PJA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PAGGYQTITG RRYGRRHAYV SFKPCMTRHE RSLGRAGDDY EVLELDDVPK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Pja2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 645 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PJA2

Target: PJA2 (Praja Ring Finger 2 (PJA2))

Alternative Name: Pja2 (PJA2 Products)

Synonyms: PJA2 antibody, AI447901 antibody, AL022700 antibody, Neurodap1 antibody, mKIAA0438 antibody, RNF131 antibody, praja2 antibody, praja ring finger ubiquitin ligase 2 antibody, PJA2 antibody, Pja2 antibody

Background: Pja2 has E2-dependent E3 ubiquitin-protein ligase activity. Pja2 is responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Pja2 is essential for PKA-mediated long-term memory processes.
Alias Symbols: AI447901, AL022700, MGC27629, Neurodap1, mKIAA0438
Protein Size: 645

Molecular Weight: 71 kDa

Gene ID: 224938

NCBI Accession: NM_144859, NP_659108