FBXO21 antibody (N-Term)

Catalog No. ABIN2774725

Product Details anti-FBXO21 Antibody

Target: FBXO21 (F-Box Protein 21 (FBXO21))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KEQFRVRWPS LMKHYSPTDY VNWLEEYKVR QKAGLEARKI VASFSKRFFS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO21. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO21

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO21

Target: FBXO21 (F-Box Protein 21 (FBXO21))

Alternative Name: FBXO21 (FBXO21 Products)

Synonyms: FBX21 antibody, 2810425J22Rik antibody, AU016673 antibody, mKIAA0875 antibody, si:ch211-42a13.2 antibody, F-box protein 21 antibody, FBXO21 antibody, Fbxo21 antibody, fbxo21 antibody

Background: FBXO21 contains 1 F-box domain. It is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DKFZp434G058, FBX21, FLJ90233, KIAA0875, MGC26682
Protein Interaction Partner: TP53, CDKN1A, SUMO1, SMURF1, NEDD8, UBC, COPS5, COPS6, CUL1, ELAVL1, CNTNAP4, TERF2, TERF1,
Protein Size: 621

Molecular Weight: 71 kDa

Gene ID: 23014

NCBI Accession: NM_015002, NP_055817

UniProt: O94952