MARCH7 antibody (Middle Region)

Catalog No. ABIN2774777

Product Details anti-MARCH7 Antibody

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSMSSTFFSR RSSQDSLNTR SLNSENSYVS PRILTASQSR SNVPSASEVP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MARCH7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARCH7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 704 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARCH7

Target: MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase (MARCH7))

Alternative Name: MARCH7 (MARCH7 Products)

Synonyms: AXO antibody, AXOT antibody, MARCH-VII antibody, RNF177 antibody, Mar-07 antibody, MARCH7 antibody, axot antibody, axotrophin antibody, march-vii antibody, rnf177 antibody, DKFZp468P155 antibody, Axo antibody, Axot antibody, Gtrgeo17 antibody, membrane associated ring-CH-type finger 7 antibody, membrane associated ring-CH-type finger 7 S homeolog antibody, membrane-associated ring finger (C3HC4) 7 antibody, MARCH7 antibody, march7.S antibody, march7 antibody, March7 antibody

Background: MARCH7 is an E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: AXO, AXOT, DKFZP586F1122, MARCH-VII, RNF177
Protein Interaction Partner: MARCH7, UBE2M, UBE2N, UBE2E1, UBE2D3, UBE2D2, UBE2D1, PPP3CB, PPP3CA, MAPT, UBC, UBE2K, USP7, TRIM65, RNF111, USP9X, VAV2,
Protein Size: 704

Molecular Weight: 78 kDa

Gene ID: 64844

NCBI Accession: NM_022826, NP_073737

UniProt: Q9H992