F-Box Protein 11 (FBXO11) (Middle Region) antibody

Details for Product No. ABIN2774788, Supplier: Log in to see
Antigen
  • fbxo11
  • im:6906507
  • wu:fj83f06
  • zgc:153171
  • MGC84634
  • FBXO11
  • Fbxo11
  • DKFZp459P2410
  • FBX11
  • PRMT9
  • UBR6
  • VIT1
  • C80048
  • Jf
  • Vit1
  • F-box protein 11
  • F-box protein 11a
  • F-box only protein 11
  • FBXO11
  • fbxo11a
  • fbxo11
  • CpipJ_CPIJ009919
  • CpipJ_CPIJ017549
  • Bm1_52225
  • LOAG_02072
  • Fbxo11
  • LOC100351392
Alternatives
anti-Human F-Box Protein 11 antibody for Immunofluorescence (fixed cells)
Epitope
Middle Region
12
10
8
5
5
4
4
4
3
3
3
3
3
1
1
1
Reactivity
Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
80
27
26
4
4
4
3
3
3
3
3
2
2
1
1
1
Host
Rabbit
59
21
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
62
32
16
13
12
10
6
4
2
1
1
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FBXO11
Blocking Peptide Blocking peptide for this product available: ABIN976727
Sequence HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ
Predicted Reactivity Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against FBXO11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FBXO11 (FBXO11 Antibody Abstract)
Background FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBX11, FLJ12673, MGC44383, PRMT9, UG063H01, VIT1, UBR6
Protein Interaction Partner: SKP1, ERN1, DTL, CUL1, EED, UBC, NEDD8, COPS5, COPS6, ELAVL1, USP16, HDAC6, BCL6, RBX1, TP53,
Protein Size: 843
Molecular Weight 94 kDa
Gene ID 80204
NCBI Accession NM_025133, NP_079409
UniProt Q6DF73
Research Area Proteolysis / Ubiquitin
Pathways Sensory Perception of Sound
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 843 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-F-Box Protein 11 (FBXO11) (Middle Region) antibody (ABIN2774788) WB Suggested Anti-FBXO11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Chromatin Immunoprecipitation (ChIP) image for anti-F-Box Protein 11 (FBXO11) (Middle Region) antibody (ABIN2774788) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
Background publications Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, 2008 (PubMed).