PCGF6 antibody (Middle Region)

Catalog No. ABIN2774797

Product Details anti-PCGF6 Antibody

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TQPLYNISAN EGTGHFKPLE KKFVRVSGEA TIGHVEKFLR RKMGLDPACQ

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PCGF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCGF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCGF6

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Alternative Name: PCGF6 (PCGF6 Products)

Synonyms: im:7144322 antibody, si:ch211-67n3.7 antibody, MBLR antibody, RNF134 antibody, 4933407A11Rik antibody, AI604840 antibody, Rnf134 antibody, polycomb group ring finger 6 antibody, PCGF6 antibody, pcgf6 antibody, Pcgf6 antibody

Background: The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MBLR, MGC15678, MGC17541, RNF134
Protein Interaction Partner: EED, RNF2, CBX8, CBX7, CBX6, UBC, HSP90AA1, USP21, USP2, RING1, PEX10, BMI1, PCGF6, RAD18, WDR5, YAF2, TFDP1, MAX, HDAC1, E2F6, CBX3, L3MBTL2, RYBP, MGA, KDM5D, ELAVL1, SS18L1, UBE2U, CDK7,
Protein Size: 275

Molecular Weight: 30 kDa

Gene ID: 84108

NCBI Accession: NM_032154, NP_115530