GJA4 antibody (Middle Region)

Catalog No. ABIN2774856

Product Details anti-GJA4 Antibody

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: QKEGELRALP AKDPQVERAL AAVERQMAKI SVAEDGRLRI RGALMGTYVA

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against GJA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJA4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 333 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJA4

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Alternative Name: GJA4 (GJA4 Products)

Synonyms: AU020209 antibody, AW558810 antibody, Cnx37 antibody, Cx37 antibody, Gja-4 antibody, CXN37 antibody, CX37 antibody, Cx39 antibody, ggCx39 antibody, cx41 antibody, gja4 antibody, gap junction protein alpha 4 antibody, gap junction protein, alpha 4 antibody, gap junction protein, alpha 4, 37kDa antibody, gap junction protein alpha 4 L homeolog antibody, GJA4 antibody, Gja4 antibody, gja4.L antibody

Background: GJA4 is a member of the connexin family. The protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CX37
Protein Size: 333

Molecular Weight: 37 kDa

Gene ID: 2701

NCBI Accession: NM_002060, NP_002051

UniProt: P35212

Pathways: Cell-Cell Junction Organization