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MCM5 antibody (N-Term)

MCM5 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774889
  • Target See all MCM5 Antibodies
    MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
    Binding Specificity
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 62
    • 32
    • 19
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Horse
    Host
    • 57
    • 5
    Rabbit
    Clonality
    • 48
    • 14
    Polyclonal
    Conjugate
    • 33
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM5 antibody is un-conjugated
    Application
    • 44
    • 20
    • 16
    • 16
    • 13
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MSGFDDPGIF YSDSFGGDAQ ADEGQARKSQ LQRRFKEFLR QYRVGTDRTG
    Predicted Reactivity
    Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against MCM5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human MCM5
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    Discover our top product MCM5 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 734 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
    Alternative Name
    MCM5 (MCM5 Products)
    Synonyms
    23.m06024 antibody, cdc46 antibody, xmcm5 antibody, CDC46 antibody, P1-CDC46 antibody, Afu5g02520 antibody, NCU01171.1 antibody, AA617332 antibody, AI324988 antibody, AL033333 antibody, Cdc46 antibody, Mcmd5 antibody, mCD46 antibody, mCDC46 antibody, mcm5 antibody, wu:fb34a06 antibody, CG4082 antibody, DmCDC46 antibody, DmCDC465 antibody, DmMCM5 antibody, DmMcm5 antibody, DmeMCM5 antibody, Dmel\\CG4082 antibody, MCM5 antibody, McM5 antibody, PCR4 antibody, DNA replication licensing factor MCM5 antibody, minichromosome maintenance complex component 5 S homeolog antibody, minichromosome maintenance complex component 5 antibody, DNA replication licensing factor Mcm5 antibody, DNA replication licensing factor mcm5 antibody, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) antibody, minichromosome maintenance complex component 5 L homeolog antibody, Minichromosome maintenance 5 antibody, DNA replication licensing factor mcm-5 antibody, BBOV_IV010040 antibody, mcm5.S antibody, MCM5 antibody, AFUA_5G02520 antibody, NCU01171 antibody, PVX_084615 antibody, LOC5576119 antibody, CpipJ_CPIJ008678 antibody, Bm1_24480 antibody, CMU_022890 antibody, Mcm5 antibody, mcm5 antibody, TP01_0722 antibody, mcm5.L antibody, mcm-5 antibody
    Background
    The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
    Alias Symbols: CDC46, P1-CDC46
    Protein Interaction Partner: KRTAP10-7, RBPMS, SUMO2, SUMO3, MCMBP, UBC, RNF2, NEK9, MCM3, HSP90AB1, HSP90AA1, FKBP5, MAGED2, CAP1, BAG3, CD81, IGSF8, TCEA1, PNKP, VCAM1, ORC5, ORC1, MCM7, MCM2, ITGA4, FN1, CDKN2A, CDC5L, NOTCH1, MYBBP1A, U2AF1, MCM6, MCM4, HNRNPU, APP, FBXO6, NEDD8,
    Protein Size: 734
    Molecular Weight
    82 kDa
    Gene ID
    4174
    NCBI Accession
    NM_006739, NP_006730
    UniProt
    P33992
    Pathways
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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