GJD2 antibody (Middle Region)

Catalog No. ABIN2774908

Product Details anti-GJD2 Antibody

Target: GJD2 (Gap Junction Protein, delta 2, 36kDa (GJD2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NTSKETEPDC LEVKELTPHP SGLRTASKSK LRRQEGISRF YIIQVVFRNA

Predicted Reactivity: Cow: 100%, Dog: 88%, Guinea Pig: 88%, Horse: 88%, Human: 100%, Mouse: 88%, Rabbit: 86%, Rat: 88%

Characteristics: This is a rabbit polyclonal antibody against CX36. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CX36

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 321 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJD2

Target: GJD2 (Gap Junction Protein, delta 2, 36kDa (GJD2))

Alternative Name: CX36 (GJD2 Products)

Synonyms: CX36 antibody, GJA9 antibody, Cx35.1 antibody, Cx36 antibody, GJD2 antibody, Gja9 antibody, connexin36 antibody, cx36 antibody, gap junction protein delta 2 antibody, gap junction protein, delta 2 antibody, GJD2 antibody, Gjd2 antibody

Background: GJA9, also called connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. See GJB2 (MIM 121011) for additional background information on connexins.[supplied by OMIM].
Alias Symbols: CX36, GJA9
Protein Size: 321

Molecular Weight: 35 kDa

Gene ID: 57369

NCBI Accession: NM_020660, NP_065711

UniProt: Q9UKL4