BRAP antibody (Middle Region)

Catalog No. ABIN2774925

Product Details anti-BRAP Antibody

Target: BRAP (BRCA1 Associated Protein (BRAP))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Rat, Cow, Horse, Mouse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRAP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YLETQQKINH LPAETRQEIQ EGQINIAMAS ASSPASSGGS GKLPSRKGRS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against BRAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRAP

Target: BRAP (BRCA1 Associated Protein (BRAP))

Alternative Name: BRAP (BRAP Products)

Synonyms: imp antibody, MGC68778 antibody, zgc:92894 antibody, BRAP antibody, BRAP2 antibody, IMP antibody, RNF52 antibody, 3010002G07Rik antibody, BRCA1 associated protein S homeolog antibody, BRCA1 associated protein antibody, BRCA1-associated protein antibody, brca1-associated protein antibody, brap.S antibody, brap antibody, BRAP antibody, NAEGRDRAFT_81654 antibody, CC1G_00971 antibody, CpipJ_CPIJ003557 antibody, Tsp_05101 antibody, LOC100282389 antibody, Brap antibody

Background: The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm.
Alias Symbols: BRAP2, IMP, RNF52
Protein Interaction Partner: SYNE2, HMG20A, UBC, NUMA1, TRIM41, TRIM55, TRIM8, CUL1, BRAP, NEDD8, USP15, USP4, KSR1, CUL2, RAF1, MAP2K1, NFKBIB, IKBKB, BRAF, HRAS, CDKN1A, TWIST1, UBE2H, CNKSR1, DDB1, CENPF, BRCA1, CDC14A,
Protein Size: 592

Molecular Weight: 67 kDa

Gene ID: 8315

NCBI Accession: NM_006768, NP_006759

UniProt: Q7Z569