CREBZF antibody (C-Term)

Catalog No. ABIN2774979

Product Details anti-CREBZF Antibody

Target: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREBZF antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TSLFRDSPAG DHDYALPVGK QKQDLLEEDD SAGGVCLHVD KDKVSVEFCS

Predicted Reactivity: Cow: 85%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CREBZF. It was validated on Western Blot.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CREBZF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 272 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CREBZF

Target: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Alternative Name: CREBZF (CREBZF Products)

Synonyms: SMILE antibody, ZF antibody, 1110034C16Rik antibody, 6330417B10Rik antibody, LAZip antibody, LAZipII antibody, Zf antibody, RGD1565584 antibody, CREB/ATF bZIP transcription factor antibody, CREBZF antibody, Crebzf antibody

Background: CREBZF strongly activates transcription when bound to HCFC1. CREBZF suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. It also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. It is able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Alias Symbols: ZF, SMILE
Protein Interaction Partner: TTC23, CTNNBL1, ACYP2, TP53, CREBZF, XBP1, NFE2L1, ATF6B, ATF4, HCFC1, ZNF512B, CREB3L3, PPARGC1A, ELAVL1, UBC,
Protein Size: 272

Molecular Weight: 29 kDa

Gene ID: 58487

NCBI Accession: NM_001039618

UniProt: Q9NS37