LASS5 antibody (N-Term)

Catalog No. ABIN2775078

Product Details anti-LASS5 Antibody

Target: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Horse, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASS5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PCALCIGIED SGPYQAQPNA ILEKVFISIT KYPDKKRLEG LSKQLDWNVR

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LASS5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LASS5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 392 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LASS5

Target: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Alternative Name: LASS5 (LASS5 Products)

Synonyms: lass5 antibody, trh4 antibody, LASS5 antibody, Trh4 antibody, 2310081H14Rik antibody, AU045339 antibody, AW544927 antibody, Lass5 antibody, ceramide synthase 5 antibody, ceramide synthase 5 S homeolog antibody, CERS5 antibody, cers5 antibody, cers5.S antibody, Cers5 antibody

Background: LASS5 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When it is overexpressed in cells it is involved in the production of sphingolipids containing mainly only one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.
Alias Symbols: CerS5, FLJ25304, MGC45411, Trh4, LASS5
Protein Interaction Partner: UBC,
Protein Size: 392

Molecular Weight: 46 kDa

Gene ID: 91012

NCBI Accession: NM_147190, NP_671723

UniProt: Q8N5B7