DDX6 antibody (N-Term)

Catalog No. ABIN2775194

Product Details anti-DDX6 Antibody

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTLKLPPKDL RIKTSDVTST KGNEFEDYCL KRELLMGIFE MGWEKPSPIQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DDX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 472 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX6

Target: DDX6 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6))

Alternative Name: DDX6 (DDX6 Products)

Synonyms: si:ch211-147p17.1 antibody, P54H antibody, Xp54 antibody, hlr2 antibody, me31b antibody, p54 antibody, rck antibody, HLR2 antibody, P54 antibody, RCK antibody, p54h antibody, RGD1564560 antibody, 1110001P04Rik antibody, E230023J21Rik antibody, mRCK/P54 antibody, DEAD-box helicase 6 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 6 antibody, DEAD-box helicase 6 L homeolog antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 antibody, DDX6 antibody, ddx6 antibody, ddx6.L antibody, Ddx6 antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX6 encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.
Alias Symbols: P54, RCK, HLR2
Protein Interaction Partner: EDC3, BIRC7, EIF4ENIF1, RUNDC3A, SDCCAG3, IKZF1, CALCOCO2, ZNF24, TCF4, VPS52, TRIM27, NONO, TRIM37, GOLGA2, AES, ZBTB8A, KRTAP10-3, KRTAP10-8, BEND7, KRT40, PNMA5, CEP70, DCP1B, DCP1A, BAG4, UBC, FAM195B, PATL1, LSM14B, LSM12, FAM195A, NUFIP2, ATXN2L, G3
Protein Size: 472

Molecular Weight: 52 kDa

Gene ID: 1656

NCBI Accession: NM_004397, NP_004388

UniProt: P26196

Pathways: Ribonucleoprotein Complex Subunit Organization