DHX8 antibody (N-Term)
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- Target See all DHX8 Antibodies
- DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DHX8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VKNGAEFTDS LISNLLRLIQ TMRPPAKPST SKDPVVKPKT EKEKLKELFP
- Predicted Reactivity
- Cow: 100%, Dog: 88%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against DHX8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human DHX8
- Top Product
- Discover our top product DHX8 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1220 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))
- Alternative Name
- DHX8 (DHX8 Products)
- Synonyms
- LRRGT00035 antibody, DHX8 antibody, im:7153552 antibody, DDX8 antibody, HRH1 antibody, PRP22 antibody, PRPF22 antibody, Ddx8 antibody, mDEAH6 antibody, mKIAA4096 antibody, DEAH-box helicase 8 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 8 antibody, Dhx8 antibody, DHX8 antibody, dhx8 antibody
- Background
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Alias Symbols: DDX8, HRH1, PRP22, PRPF22
Protein Interaction Partner: NUDCD1, UBC, LIN28A, XRN2, SRPK2, SRPK1, BAG3, PRPF38A, NKAP, ISY1, PRPF40A, ZCCHC10, RBMX2, SAP30BP, CHERP, RBM7, THOC1, MFAP1, DHX8, NOTCH1, KANSL1, PHF5A, MYPN, POLR1B, CRNKL1, TAF9, SMAD3, SMAD2, CAND1, CUL3, SIRT7, USP12,
Protein Size: 1220 - Molecular Weight
- 139 kDa
- Gene ID
- 1659
- NCBI Accession
- NM_004941, NP_004932
- UniProt
- Q14562
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