IGFALS antibody (Middle Region)

Catalog No. ABIN2775293

Product Details anti-IGFALS Antibody

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFALS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DCGCPLKALR DFALQNPSAV PRFVQAICEG DDCQPPAYTY NNITCASPPE

Predicted Reactivity: Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IGFALS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IGFALS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 605 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGFALS

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Alternative Name: IGFALS (IGFALS Products)

Synonyms: ALS antibody, Albs antibody, mKIAA4111 antibody, Als antibody, insulin like growth factor binding protein acid labile subunit antibody, insulin like growth factor binding protein acid labile subunit L homeolog antibody, insulin-like growth factor binding protein, acid labile subunit antibody, IGFALS antibody, igfals.L antibody, Igfals antibody

Background: Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.
Alias Symbols: ALS
Protein Interaction Partner: PDCD6, IGF1, IGFBP5, IGFBP3,
Protein Size: 605

Molecular Weight: 63 kDa

Gene ID: 3483

NCBI Accession: NM_004970, NP_004961

UniProt: P35858