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Follistatin antibody (Middle Region)

FST Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Goat, Sheep, Guinea Pig, Cow, Zebrafish (Danio rerio), Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775336
  • Target See all Follistatin (FST) Antibodies
    Follistatin (FST)
    Binding Specificity
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 64
    • 25
    • 21
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Dog, Horse, Rabbit, Goat, Sheep, Guinea Pig, Cow, Zebrafish (Danio rerio), Pig
    Host
    • 47
    • 16
    • 2
    Rabbit
    Clonality
    • 52
    • 13
    Polyclonal
    Conjugate
    • 41
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Follistatin antibody is un-conjugated
    Application
    • 46
    • 35
    • 26
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ALLKARCKEQ PELEVQYQGR CKKTCRDVFC PGSSTCVVDQ TNNAYCVTCN
    Predicted Reactivity
    Cow: 92%, Dog: 100%, Goat: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against FST. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FST
    Top Product
    Discover our top product FST Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 317 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Follistatin (FST)
    Alternative Name
    FST (FST Products)
    Synonyms
    CG12955 antibody, CG12956 antibody, CG33466 antibody, Dmel\\CG33466 antibody, Fol1 antibody, dFS antibody, dFol1 antibody, dfs antibody, fs antibody, FS antibody, foll antibody, xfs antibody, FST antibody, fst antibody, AL033346 antibody, FOL1 antibody, Fst-288 antibody, RATFOL1 antibody, cb446 antibody, fd07h10 antibody, fst1 antibody, wu:fd07h10 antibody, Follistatin antibody, follistatin antibody, follistatin L homeolog antibody, follistatin a antibody, Fs antibody, fst antibody, FST antibody, LOC100141662 antibody, fst.L antibody, Fst antibody, fsta antibody
    Background
    Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
    Alias Symbols: FS
    Protein Interaction Partner: INHBA, BMPR2, BMPR1A, C8orf33, TK1, MEST, INHBE, INHA, FN1, BMP5, TXN,
    Protein Size: 317
    Molecular Weight
    35 kDa
    Gene ID
    10468
    NCBI Accession
    NM_006350, NP_006341
    UniProt
    B5BU94
    Pathways
    Negative Regulation of Hormone Secretion
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