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HAO1 antibody (C-Term)

HAO1 Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775438
  • Target See all HAO1 Antibodies
    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
    Binding Specificity
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 29
    • 25
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae
    Host
    • 31
    • 6
    Rabbit
    Clonality
    • 32
    • 5
    Polyclonal
    Conjugate
    • 19
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HAO1 antibody is un-conjugated
    Application
    • 24
    • 15
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    GLNGILVSNH GARQLDGVPA TIDVLPEIVE AVEGKVEVFL DGGVRKGTDV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against HAO1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human HAO1
    Top Product
    Discover our top product HAO1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 370 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Williams, Cregeen, Rumsby: "Identification and expression of a cDNA for human glycolate oxidase." in: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 246-8, (2000) (PubMed).

  • Target
    HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
    Alternative Name
    HAO1 (HAO1 Products)
    Synonyms
    hao1 antibody, GOX antibody, GOX1 antibody, HAOX1 antibody, Gox1 antibody, XDH1 antibody, Hao-1 antibody, hydroxyacid oxidase 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog antibody, hydroxyacid oxidase 1, liver antibody, CpipJ_CPIJ013711 antibody, THEYE_A0075 antibody, hao1 antibody, HAO1 antibody, hao1.L antibody, Hao1 antibody
    Background
    Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
    Alias Symbols: GOX, GOX1, HAOX1
    Protein Interaction Partner: PEX5, HCVgp1,
    Protein Size: 370
    Molecular Weight
    41 kDa
    Gene ID
    54363
    NCBI Accession
    NM_017545, NP_060015
    UniProt
    Q9UJM8
    Pathways
    Monocarboxylic Acid Catabolic Process
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