BMP2K antibody (Middle Region)

Catalog No. ABIN2775439

Product Details anti-BMP2K Antibody

Target: BMP2K (BMP2 Inducible Kinase (BMP2K))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP2K antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VKVLAPGEFG NHRPKGALRP GNGPEILLGQ GPPQQPPQQH RVLQQLQQGD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 83%, Human: 100%, Mouse: 100%, Rat: 92%, Yeast: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against BMP2K. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BMP2K

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 662 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMP2K

Target: BMP2K (BMP2 Inducible Kinase (BMP2K))

Alternative Name: BMP2K (BMP2K Products)

Synonyms: zgc:101641 antibody, BIKE antibody, 4933417M22Rik antibody, AA673486 antibody, AV128808 antibody, BMP2 inducible kinase antibody, BMP-2 inducible kinase antibody, BMP2K antibody, bmp2k antibody, Bmp2k antibody

Background: BMP2K is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. BMP2K is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BIKE, DKFZp434K0614, DKFZp434P0116, HRIHFB2017
Protein Interaction Partner: FN1, EPS15, AP2M1, ABL1, TERF2, TERF1, KDM5B, MBP,
Protein Size: 662

Molecular Weight: 74 kDa

Gene ID: 55589

NCBI Accession: NM_017593, NP_060063

UniProt: Q4W5H2