Gasdermin B antibody (N-Term)

Catalog No. ABIN2775462

Product Details anti-Gasdermin B Antibody

Target: Gasdermin B (GSDMB)

Binding Specificity: N-Term

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gasdermin B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HLVGEKRTFF GCRHYTTGLT LMDILDTDGD KWLDELDSGL QGQKAEFQIL

Predicted Reactivity: Horse: 100%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GSDML. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSDML

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 394 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Gasdermin B antibody (ABIN2775462)

Adams, Leavitt, Holmes: "Strabismus surgery for internuclear ophthalmoplegia with exotropia in multiple sclerosis." in: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, Vol. 13, Issue 1, pp. 13-5, (2009) (PubMed).

Target Details for Gasdermin B

Target: Gasdermin B (GSDMB)

Alternative Name: GSDML (GSDMB Products)

Synonyms: GSDML antibody, PRO2521 antibody, gasdermin B antibody, GSDMB antibody

Background: GSDML belongs to the gasdermin family.GSDML may play a role as secretory or metabolic product involved in secretory pathway. It may also play a role in achieving and maintaining the final differentiation state of epithelial cells.
Alias Symbols: PP4052, PRO2521, GSDML
Protein Interaction Partner: SERPINA1, ORM1, IGFBP2, HIVEP1, AGT, PEBP1, APP,
Protein Size: 394

Molecular Weight: 45 kDa

Gene ID: 55876

NCBI Accession: NM_018530, NP_061000

UniProt: Q8TAX9