CHIA antibody (N-Term)

Catalog No. ABIN2775494

Product Details anti-CHIA Antibody

Target: CHIA (Chitinase, Acidic (CHIA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHIA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MVSTPENRQT FITSVIKFLR QYEFDGLDFD WEYPGSRGSP PQDKHLFTVL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CHIA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHIA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 368 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CHIA antibody (ABIN2775494)

Strobel, Roswag, Becker, Trenczek, Encarnação: "Insectivorous bats digest chitin in the stomach using acidic mammalian chitinase." in: PLoS ONE, Vol. 8, Issue 9, pp. e72770, (2013) (PubMed).

Fukushima, Nashida, Haga-Tsujimura, Mataga: "Chitinase expression in parotid glands of non-obese diabetic mice." in: Oral diseases, Vol. 18, Issue 5, pp. 506-12, (2012) (PubMed).

Target Details for CHIA

Target: CHIA (Chitinase, Acidic (CHIA))

Alternative Name: CHIA (CHIA Products)

Synonyms: chia-a antibody, AMCASE antibody, CHIT2 antibody, TSA1902 antibody, 2200003E03Rik antibody, AMCase antibody, YNL antibody, CHIA antibody, chioIIa antibody, fa55g10 antibody, wu:fa55g10 antibody, zgc:63792 antibody, acidic mammalian chitinase antibody, chitinase, acidic antibody, chitinase, acidic S homeolog antibody, chitinase-M31, acidic antibody, chitinase, acidic 1 antibody, chitinase, acidic.4 antibody, LOC703284 antibody, CHIA antibody, LOC100600050 antibody, chia.S antibody, CHIA-M31 antibody, Chia1 antibody, Chia antibody, chia.4 antibody

Background: CHIA belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. It contains 1 chitin-binding type-2 domain. The protein degrades chitin and chitotriose. And it may participate in the defense against nematodes and other pathogens.
Alias Symbols: 2200003E03Rik, AMCase, CHIT2, DKFZp313J1722, RP5-1125M8.1, TSA1902, AMCASE
Protein Size: 368

Molecular Weight: 40 kDa

Gene ID: 27159

NCBI Accession: NM_021797, NP_068569

UniProt: Q9BZP6