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PPP4R2 antibody (C-Term)

PPP4R2 Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Dog, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775552
  • Target See all PPP4R2 Antibodies
    PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
    Binding Specificity
    • 10
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Horse, Pig, Dog, Rabbit
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP4R2 antibody is un-conjugated
    Application
    • 24
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DSRCTRQHCT EEDEEEDEEE EEESFMTSRE MIPERKNQEK ESDDALTVNE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PPP4R2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PPP4R2
    Top Product
    Discover our top product PPP4R2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 417 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
    Alternative Name
    PPP4R2 (PPP4R2 Products)
    Synonyms
    PP4R2 antibody, BE691708 antibody, C230060M08Rik antibody, ppp4r2 antibody, fe11b04 antibody, wu:fe11b04 antibody, ppp4r2-B antibody, wu:fa17h08 antibody, wu:fc23g05 antibody, protein phosphatase 4 regulatory subunit 2 antibody, protein phosphatase 4, regulatory subunit 2 antibody, protein phosphatase 4, regulatory subunit 2a antibody, protein phosphatase 4 regulatory subunit 2 S homeolog antibody, protein phosphatase 4 regulatory subunit 2 L homeolog antibody, protein phosphatase 4, regulatory subunit 2b antibody, PPP4R2 antibody, Ppp4r2 antibody, ppp4r2a antibody, ppp4r2.S antibody, ppp4r2 antibody, ppp4r2.L antibody, ppp4r2b antibody
    Background
    PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
    Alias Symbols: MGC131930, PP4R2
    Protein Interaction Partner: UBC, PAAF1, SMEK1, SF3A1, CCDC6, VASP, CCT3, PSMA1, INPPL1, AMPD2, LRRC47, DSTN, PLIN3, NUBP2, TPM1, TRA2B, IGBP1, CLNS1A, PPP4C, SRRM2, TIPRL, SMEK2, GEMIN4, DDX20,
    Protein Size: 417
    Molecular Weight
    47 kDa
    Gene ID
    151987
    NCBI Accession
    NM_174907, NP_777567
    UniProt
    Q9NY27
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