Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

LIN7C antibody (N-Term)

LIN7C Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775625
  • Target See all LIN7C Antibodies
    LIN7C (Lin-7 Homolog C (LIN7C))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 36
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 36
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIN7C antibody is un-conjugated
    Application
    • 36
    • 17
    • 16
    • 13
    • 13
    • 8
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MAALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against LIN7C. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LIN7C
    Top Product
    Discover our top product LIN7C Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 197 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LIN7C (Lin-7 Homolog C (LIN7C))
    Alternative Name
    LIN7C (LIN7C Products)
    Synonyms
    LIN7C antibody, fb75b09 antibody, wu:fb75b09 antibody, zgc:101881 antibody, LIN-7-C antibody, LIN-7C antibody, MALS-3 antibody, MALS3 antibody, VELI3 antibody, 9130007B12Rik antibody, AI303698 antibody, AU019331 antibody, AW125731 antibody, D2Ertd520e antibody, Veli3 antibody, lin-7 homolog C, crumbs cell polarity complex component antibody, lin-7 homolog C L homeolog antibody, lin-7 homolog C (C. elegans) antibody, LIN7C antibody, lin7c.L antibody, lin7c antibody, Lin7c antibody
    Background
    LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
    Alias Symbols: FLJ11215, LIN-7-C, LIN-7C, MALS-3, VELI3, MALS3
    Protein Interaction Partner: UBC, AMOTL2, LATS2, YAP1, Wwtr1, CFTR, ELAVL1, AMOT, UIMC1, SPATA2, KCNJ12, BAIAP2, ABCA1, HTR2C, CASK, KCNJ4, DLG1, APBA1,
    Protein Size: 197
    Molecular Weight
    22 kDa
    Gene ID
    55327
    NCBI Accession
    NM_018362, NP_060832
    UniProt
    Q9NUP9
    Pathways
    Synaptic Membrane
You are here:
Support