InaD-Like (Drosophila) (INADL) (N-Term) antibody

Details for Product No. ABIN2775641, Supplier: Log in to see
Antigen
  • wu:fc76h08
  • si:dz129i22.4
  • si:busm1-129i22.4
  • Cipp
  • InaD-like
  • PATJ
  • hINADL
  • Patj
  • Inadl2
  • RGD1565362
  • InaD-like (Drosophila)
  • InaD-like
  • inadl
  • LOC100356380
  • INADL
  • Inadl
Epitope
N-Term
18
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
48
17
15
5
3
2
2
2
1
1
Host
Rabbit
28
19
1
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
18
14
13
8
7
2
2
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human INADL
Blocking Peptide Blocking peptide for this product available: ABIN978544
Sequence EVMVATLDTQ IADDAELQKY SKLLPIHTLR LGVEVDSFDG HHYISSIVSG
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against INADL. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name INADL (INADL Antibody Abstract)
Background INADL is a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Cipp, FLJ26982, PATJ, hINADL, InaD-like
Protein Interaction Partner: SUMO1, UBC, NEDD8, AMOT, SAV1, AMOTL2, LATS2, YAP1, LATS1, Wwtr1, BAI1, TP53RK, PARD3, Dlg4, ARHGAP17, SUMO2, TJP3, CRB3, PRDM16, NRXN2, ASIC3, MPP5, NLGN2, CNKSR2, PAX6, GLS2, DDX18, KIF1B, CRIPT, SCN4A, CLDN1, CACNG2, GRIN2D, MAPK12, KCNJ10, KCNJ15, KCN
Protein Size: 1801
Molecular Weight 196 kDa
Gene ID 10207
NCBI Accession NM_176877, NP_795352
UniProt Q8NI35
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1801 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-InaD-Like (Drosophila) (INADL) (N-Term) antibody (ABIN2775641) WB Suggested Anti-INADL Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Product cited in: Storrs, Silverstein: "PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6." in: Journal of virology, Vol. 81, Issue 8, pp. 4080-90, 2007 (PubMed).

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