RAG1 antibody (C-Term)
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- Target See all RAG1 Antibodies
- RAG1 (Recombination Activating Gene 1 (RAG1))
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Binding Specificity
- C-Term
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Reactivity
- Mouse, Rat, Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RAG1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
- Predicted Reactivity
- Horse: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Rag1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product RAG1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1040 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RAG1 (Recombination Activating Gene 1 (RAG1))
- Alternative Name
- Rag1 (RAG1 Products)
- Synonyms
- RAG-1 antibody, rag1 antibody, RNF74 antibody, Rag-1 antibody, rag-1 antibody, rag1a antibody, recombination activating 1 antibody, recombination activating gene 1 antibody, recombination activating gene 1 S homeolog antibody, Rag1 antibody, RAG1 antibody, rag1 antibody, rag1.S antibody
- Background
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As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
Alias Symbols: Rag-1
Protein Interaction Partner: Gmeb1, Sf3a2, Kpna2, Rag1, UBE2C, UBE2H, UBE2E1, UBE2D2, UBE2D1, UBC, CDC34, Trav6-3, Rel, Nfkb1, Rela,
Protein Size: 1040 - Molecular Weight
- 119 kDa
- Gene ID
- 19373
- NCBI Accession
- NM_009019, NP_033045
- UniProt
- P15919
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