RCHY1 antibody (N-Term)
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- Target See all RCHY1 Antibodies
- RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, Dog, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RCHY1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KLYTCRLCHD NNEDHQLDRF KVKEVQCINC EKIQHAQQTC EECSTLFGEY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against RCHY1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RCHY1
- Top Product
- Discover our top product RCHY1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 200 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
- Alternative Name
- RCHY1 (RCHY1 Products)
- Synonyms
- ARNIP antibody, CHIMP antibody, PIRH2 antibody, PRO1996 antibody, RNF199 antibody, ZNF363 antibody, Pirh2 antibody, Zfp363 antibody, Znf363 antibody, wu:fb37e07 antibody, zgc:101128 antibody, RCHY1 antibody, arnip antibody, chimp antibody, pirh2 antibody, harnip antibody, rnf199 antibody, znf363 antibody, pro1996 antibody, ring finger and CHY zinc finger domain containing 1 antibody, ring finger and CHY zinc finger domain containing 1 L homeolog antibody, RCHY1 antibody, Rchy1 antibody, rchy1 antibody, rchy1.L antibody
- Background
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RCHY1 has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZNF363, hARNIP, PIRH2E, PIRH2F
Protein Interaction Partner: MEOX2, NOTCH2NL, UBASH3B, KRTAP9-2, LIMS2, SEMA4C, WDR74, ADAMTSL4, RCHY1, PGLS, KLHL41, MDM2, TAOK2, TP53, UBC, RNF2, HOXA2, YWHAE, CDK9, DCUN1D5, RILP, TMBIM1, CHD8, USP28, C19orf80, RBM38, NLK, TMEM14C, AIG1, SERTAD1, CHEK2, PRDX4, RAB11A, FADS6, TMEM1
Protein Size: 200 - Molecular Weight
- 23 kDa
- Gene ID
- 25898
- NCBI Accession
- NM_001008925, NP_001008925
- UniProt
- Q96PM5
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