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UBE2L6 antibody (N-Term)

UBE2L6 Reactivity: Human, Rat, Mouse, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775687
  • Target See all UBE2L6 Antibodies
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Binding Specificity
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Mouse, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 35
    • 6
    Rabbit
    Clonality
    • 38
    • 3
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2L6 antibody is un-conjugated
    Application
    • 29
    • 21
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LLLPDQPPYH LKAFNLRISF PPEYPFKPPM IKFTTKIYHP NVDENGQICL
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against UBE2L6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2L6
    Top Product
    Discover our top product UBE2L6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 153 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." in: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).

  • Target
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Alternative Name
    UBE2L6 (UBE2L6 Products)
    Synonyms
    UBE2L6 antibody, RIG-B antibody, UBCH8 antibody, 2810489I21Rik antibody, Ubce8 antibody, Ubcm8 antibody, UbcM8 antibody, ubiquitin conjugating enzyme E2 L6 antibody, ubiquitin-conjugating enzyme E2L 6 antibody, UBE2L6 antibody, Ube2l6 antibody
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: MGC40331, RIG-B, UBCH8
    Protein Interaction Partner: LONRF1, FBXO31, RBCK1, ARIH2, RBX1, CUL1, SKP1, UBE2L6, UBC, SIAH2, PARK2, RNF144A, UBE3A, RAD23A, ARIH1, SPEN, ISG15, TIMM8A, RAD21, FLT3, ARHGDIA, park, SIAH1, RUNX1, RNF144B, DTX3, RNF19B, TRAF7, TRIM8, RNF122, MUL1, RNF25, RNF150, RNF125, CBLC, TOPORS
    Protein Size: 153
    Molecular Weight
    18 kDa
    Gene ID
    9246
    NCBI Accession
    NM_004223, NP_004214
    UniProt
    Q8N5D8
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