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TRIM24 antibody (Middle Region)

TRIM24 Reactivity: Human, Mouse, Cow, Rat, Horse, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775799
  • Target See all TRIM24 Antibodies
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 61
    • 23
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human, Mouse, Cow, Rat, Horse, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
    Host
    • 57
    • 5
    • 1
    Rabbit
    Clonality
    • 56
    • 7
    Polyclonal
    Conjugate
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TRIM24 antibody is un-conjugated
    Application
    • 43
    • 26
    • 13
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    QQPSISHQQP PPRLINFQNH SPKPNGPVLP PHPQQLRYPP NQNIPRQAIK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
    Characteristics
    This is a rabbit polyclonal antibody against TRIM24. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TRIM24
    Top Product
    Discover our top product TRIM24 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1050 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    Alternative Name
    TRIM24 (TRIM24 Products)
    Synonyms
    TRIM24 antibody, PTC6 antibody, RNF82 antibody, TF1A antibody, TIF1 antibody, TIF1A antibody, TIF1ALPHA antibody, hTIF1 antibody, ptc6 antibody, rnf82 antibody, tf1a antibody, tif1 antibody, tif1a antibody, tif1alpha antibody, A130082H20Rik antibody, AI447469 antibody, D430004I05Rik antibody, TIF1-alpha antibody, TIF1alpha antibody, Tif1a antibody, tripartite motif containing 24 antibody, transcription intermediary factor 1-alpha antibody, tripartite motif containing 24 S homeolog antibody, tripartite motif-containing 24 antibody, TRIM24 antibody, trim24 antibody, LOC100548578 antibody, trim24.S antibody, Trim24 antibody
    Background
    The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
    Protein Interaction Partner: UBC, SUMO2, SUMO3, TRIM33, TP53, SUMO1, RNF2, RNF181, RNF141, ESR2, BRCA1, SF3B1, SF3B2, SNRPA, NONO, CDK12, NCOA1, TRIM8, NR3C2, ESR1, HIST1H3E, HIST2H4B, HIST4H4, HIST1H3F, HIST2H4A, HIST1H4L, HIST1H4E, HIST1H4B, HIST1H4H, HIST1H4C, HIST1H4J, HIST1H4K,
    Protein Size: 1050
    Molecular Weight
    117 kDa
    Gene ID
    8805
    NCBI Accession
    NM_015905, NP_056989
    UniProt
    O15164
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