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TFB2M antibody (N-Term)

TFB2M Reactivity: Human, Rat, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775816
  • Target See all TFB2M Antibodies
    TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
    Binding Specificity
    • 10
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Horse, Rabbit
    Host
    • 24
    • 5
    • 3
    Rabbit
    Clonality
    • 30
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    This TFB2M antibody is un-conjugated
    Application
    • 26
    • 23
    • 17
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD
    Predicted Reactivity
    Horse: 100%, Human: 100%, Rabbit: 83%, Rat: 85%
    Characteristics
    This is a rabbit polyclonal antibody against TFB2M. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M
    Top Product
    Discover our top product TFB2M Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 396 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
    Alternative Name
    TFB2M (TFB2M Products)
    Synonyms
    CG3910 antibody, Dmel\\CG3910 antibody, TFB2 antibody, d-TF2BM antibody, d-mtTFB2 antibody, TFB2M antibody, sb:cb857 antibody, hkp1 antibody, Hkp1 antibody, mtTFB2 antibody, mitochondrial transcription factor B2 antibody, transcription factor B2, mitochondrial antibody, mtTFB2 antibody, TFB2M antibody, tfb2m antibody, Tfb2m antibody
    Background
    TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
    Alias Symbols: FLJ22661, FLJ23182, Hkp1, mtTFB2
    Protein Interaction Partner: UBC, FBXO6, C1QBP, CUL3, TFB2M, POLRMT, TFAM, PNP,
    Protein Size: 396
    Molecular Weight
    45 kDa
    Gene ID
    64216
    NCBI Accession
    NM_022366, NP_071761
    UniProt
    Q9H5Q4
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