VAX1 antibody (N-Term)

Catalog No. ABIN2775832

Product Details anti-VAX1 Antibody

Target: VAX1 (Ventral Anterior Homeobox 1 (VAX1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MFGKPDKMDV RCHSDAEAAR VSKNAHKESR ESKGAEGNLP AAFLKEPQGA

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against VAX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human Vax1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 186 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-VAX1 antibody (ABIN2775832)

Holland, Booth, Bruford: "Classification and nomenclature of all human homeobox genes." in: BMC biology, Vol. 5, pp. 47, (2008) (PubMed).

Target Details for VAX1

Target: VAX1 (Ventral Anterior Homeobox 1 (VAX1))

Alternative Name: Vax1 (VAX1 Products)

Background: VAX1 is a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. It may play an important role in the development of anterior ventral forebrain and visual system.This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-180 AK127095.1 1-180 181-201 AL731557.7 35785-35805 c 202-1186 AK127095.1 199-1183 1187-4494 AL731557.7 26205-29512 c
Alias Symbols: MGC126743, MGC126745
Protein Size: 186

Molecular Weight: 21 kDa

Gene ID: 11023

NCBI Accession: NM_199131, NP_954582

UniProt: B1AVW5