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METTL3 antibody (C-Term)

METTL3 Reactivity: Human, Rat, Mouse, Dog, Horse, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio), Goat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775894
  • Target See all METTL3 Antibodies
    METTL3 (Methyltransferase Like 3 (METTL3))
    Binding Specificity
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 29
    • 21
    • 16
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Human, Rat, Mouse, Dog, Horse, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio), Goat
    Host
    • 36
    • 2
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 24
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This METTL3 antibody is un-conjugated
    Application
    • 34
    • 13
    • 13
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    KIELFGRPHN VQPNWITLGN QLDGIHLLDP DVVARFKQRY PDGIISKPKN
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against METTL3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human METTL3
    Top Product
    Discover our top product METTL3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 580 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    METTL3 (Methyltransferase Like 3 (METTL3))
    Alternative Name
    METTL3 (METTL3 Products)
    Background
    This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
    Alias Symbols: IME4, M6A, MGC4336, MT-A70, Spo8
    Protein Interaction Partner: UBC, METTL14, UBD,
    Protein Size: 580
    Molecular Weight
    64 kDa
    Gene ID
    56339
    NCBI Accession
    NM_019852, NP_062826
    UniProt
    Q86U44
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