UHRF2 antibody (Middle Region)

Catalog No. ABIN2775913

Product Details anti-UHRF2 Antibody

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NCDAPLDDKI GAESRNWRAG KPVRVIRSFK GRKISKYAPE EGNRYDGIYK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against UHRF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UHRF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: UHRF2 (UHRF2 Products)

Synonyms: NIRF antibody, RNF107 antibody, URF2 antibody, 2310065A22Rik antibody, AI426270 antibody, AW214556 antibody, D130071B19Rik antibody, Nirf antibody, ubiquitin like with PHD and ring finger domains 2 antibody, ubiquitin-like, containing PHD and RING finger domains 2 antibody, ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog antibody, UHRF2 antibody, Uhrf2 antibody, uhrf2.L antibody

Background: UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.
Alias Symbols: DKFZp434B0920, DKFZp686G0837, MGC33463, NIRF, RNF107, RP11-472F14.2, URF2
Protein Interaction Partner: UBE2D1, UBC, TP53, UHRF2, TRIM27, E2F1, MPG, SMAD4, ZNF131, SUMO1, UBE2I, ATXN1, USP7, TWF2, TRIM8, RBCK1, TFAP4, PCNP, CDK2, CCNE1, UHRF1, EHMT2, HIST1H3A, SUMO2, DNMT3B, DNMT3A, DNMT1, CDK1, CD27, CCNB1, CCNA2, BCL2L1, CCND1, BAX, BCAR1, YY1, SKP1, RB1,
Protein Size: 802

Molecular Weight: 90 kDa

Gene ID: 115426

NCBI Accession: NM_152896, NP_690856

UniProt: Q96PU4