Kv Channel Interacting Protein 4 (KCNIP4) (N-Term) antibody

Details for Product No. ABIN2775915, Supplier: Log in to see
Antigen
  • KCHIP4.2
  • KCNIP4
  • MGC115522
  • DKFZp459M1362
  • CALP
  • KCHIP4
  • AV032399
  • Calp
  • Calp250
  • KChIP4
  • KChIP4a
  • Kchip4
  • Kv channel interacting protein 4
  • KCNIP4
  • kcnip4
  • LOC100348464
  • Kcnip4
Epitope
N-Term
15
9
9
2
2
2
2
2
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
41
29
14
5
5
4
3
1
Host
Rabbit
40
5
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
41
26
5
4
3
2
Options
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Available images

Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP4
Blocking Peptide Blocking peptide for this product available: ABIN978793
Sequence NSTKRSIKER LMKLLPCSAA KTSSPAIQNS VEDELEMATV RHRPEALELL
Predicted Reactivity Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against KCNIP4. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name KCNIP4 (KCNIP4 Antibody Abstract)
Background KCNIP4 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin.
Alias Symbols: CALP, KCHIP4
Protein Interaction Partner: APP, KCND2, PSEN2, PSEN1, KCNIP2,
Protein Size: 250
Molecular Weight 29 kDa
Gene ID 80333
NCBI Accession NM_025221, NP_079497
UniProt Q6PIL6
Research Area Neurology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 250 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Kv Channel Interacting Protein 4 (KCNIP4) (N-Term) antibody (ABIN2775915) WB Suggested Anti-KCNIP4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-Kv Channel Interacting Protein 4 (KCNIP4) (N-Term) antibody (ABIN2775915) anti-Kv Channel Interacting Protein 4 (KCNIP4) (N-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Kv Channel Interacting Protein 4 (KCNIP4) (N-Term) antibody (ABIN2775915) Human Brain
Background publications Morohashi, Hatano, Ohya, Takikawa, Watabiki, Takasugi, Imaizumi, Tomita, Iwatsubo: "Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4." in: The Journal of biological chemistry, Vol. 277, Issue 17, pp. 14965-75, 2002 (PubMed).