PSIP1 antibody (Middle Region)

Catalog No. ABIN2775928

Product Details anti-PSIP1 Antibody

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Horse, Guinea Pig, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against PSIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1 (PSIP1 Products)

Synonyms: PSIP1 antibody, im:7149861 antibody, zgc:109898 antibody, LEDGF antibody, p75 antibody, PSIP2 antibody, DFS70 antibody, PAIP antibody, p52 antibody, AA408851 antibody, AU015605 antibody, Dfs70 antibody, Ledgfa antibody, Ledgfb antibody, Psip2 antibody, Ledgf antibody, SBP75 antibody, LEDGF/p75 antibody, PC4 and SFRS1 interacting protein 1 S homeolog antibody, PC4 and SFRS1 interacting protein 1 antibody, PC4 and SFRS1 interacting protein 1a antibody, LEDGF/p75 transcription factor-like antibody, psip1.S antibody, PSIP1 antibody, psip1a antibody, psip1 antibody, Psip1 antibody

Background: PSIP1 encodes a multidomain adaptor protein that interacts with the nuclear import apparatus, lentiviral IN proteins and chromatin by means of an NLS, an IBD and additional chromatin-interacting domains.
Alias Symbols: p52, p75, PAIP, DFS70, LEDGF, PSIP2
Protein Interaction Partner: PPP2R1A, UBC, RPA3, RPA2, RPA1, HMGA2, HMGA1, WHSC1, CSNK2A1, gag-pol, ESR1, ZC3H18, FTSJ3, EXOSC5, EXOSC4, NCSTN, RRS1, SUPT16H, SAP18, THRAP3, EIF4A3, U2AF1, TPBG, SON, TRA2B, RPS24, RPS11, RPL6, CAST, SH3KBP1, MEN1, SUMO1, SUMO2, HDGF, MAPK6, KMT2A, BA
Protein Size: 530

Molecular Weight: 60 kDa

Gene ID: 11168

NCBI Accession: NM_033222, NP_150091

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization