UHRF2 antibody (N-Term)

Catalog No. ABIN2776011

Product Details anti-UHRF2 Antibody

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TIEELRERVW ALFDVRPECQ RLFYRGKQLE NGYTLFDYDV GLNDIIQLLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Uhrf2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: Uhrf2 (UHRF2 Products)

Synonyms: NIRF antibody, RNF107 antibody, URF2 antibody, 2310065A22Rik antibody, AI426270 antibody, AW214556 antibody, D130071B19Rik antibody, Nirf antibody, ubiquitin like with PHD and ring finger domains 2 antibody, ubiquitin-like, containing PHD and RING finger domains 2 antibody, ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase L homeolog antibody, UHRF2 antibody, Uhrf2 antibody, uhrf2.L antibody

Background: Uhrf2 is an E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of PCNP. It may participate in methylation-dependent transcriptional regulation. It is important for G1/S transition. Overexpression causes G1 phase cell arrest.
Alias Symbols: 2310065A22Rik, AI426270, AW214556, D130071B19Rik, Nirf
Protein Size: 803

Molecular Weight: 90 kDa

Gene ID: 109113

NCBI Accession: NM_144873, NP_659122

UniProt: Q7TMI3