CHRNA5 antibody (Middle Region)

Catalog No. ABIN2776103

Product Details anti-CHRNA5 Antibody

Target: CHRNA5 (Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DGSQVDIILE DQDVDKRDFF DNGEWEIVSA TGSKGNRTDS CCWYPYVTYS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against CHRNA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHRNA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 468 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA5

Target: CHRNA5 (Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5))

Alternative Name: CHRNA5 (CHRNA5 Products)

Synonyms: zgc:110642 antibody, LNCR2 antibody, Acra-5 antibody, Acra5 antibody, cholinergic receptor, nicotinic, alpha 5 antibody, cholinergic receptor nicotinic alpha 5 subunit antibody, cholinergic receptor nicotinic alpha 5 subunit L homeolog antibody, cholinergic receptor, nicotinic, alpha polypeptide 5 antibody, chrna5 antibody, CHRNA5 antibody, chrna5.L antibody, Chrna5 antibody

Background: Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits.
Alias Symbols: LNCR2
Protein Interaction Partner: UBC, CANX, CHRNB4,
Protein Size: 468

Molecular Weight: 53 kDa

Gene ID: 1138

NCBI Accession: NM_000745, NP_000736

UniProt: P30532