SHROOM2 antibody (Middle Region)

Catalog No. ABIN2776133

Product Details anti-SHROOM2 Antibody

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CTSPPGLSYM KAKEKTVEDL KSEELAREIV GKDKSLADIL DPSVKIKTTM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SHROOM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SHROOM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1616 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHROOM2

Target: SHROOM2 (Shroom Family Member 2 (SHROOM2))

Alternative Name: SHROOM2 (SHROOM2 Products)

Synonyms: SHROOM2 antibody, APXL antibody, apxl antibody, shrm2 antibody, HSAPXL antibody, 4832440C16 antibody, Apxl antibody, C630003H05Rik antibody, Shrm2 antibody, shroom family member 2 antibody, SHROOM2 antibody, shroom2 antibody, Shroom2 antibody

Background: SHROOM2 shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.
Alias Symbols: APXL, DKFZp781J074, FLJ39277, HSAPXL
Protein Interaction Partner: YWHAE, YWHAG,
Protein Size: 1616

Molecular Weight: 176 kDa

Gene ID: 357

NCBI Accession: NM_001649, NP_001640

UniProt: Q13796

Pathways: Cell-Cell Junction Organization, Asymmetric Protein Localization