TPCN1 antibody (N-Term)

Catalog No. ABIN2776222

Product Details anti-TPCN1 Antibody

Target: TPCN1 (Two Pore Segment Channel 1 (TPCN1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YQEAAIYLQE GENNDKFFTH PKDAKALAAY LFAHNHLFYL MELATALLLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TPCN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPCN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 816 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TPCN1

Target: TPCN1 (Two Pore Segment Channel 1 (TPCN1))

Alternative Name: TPCN1 (TPCN1 Products)

Synonyms: ATCCH1 antibody, ATTPC1 antibody, CALCIUM CHANNEL 1 antibody, FATTY ACID OXYGENATION UPREGULATED 2 antibody, FOU2 antibody, T5L23.5 antibody, two-pore channel 1 antibody, 5730403B01Rik antibody, Tpc1 antibody, mKIAA1169 antibody, TPC1 antibody, si:dkey-125i10.5 antibody, two pore segment channel 1 antibody, two-pore channel 1 antibody, two pore channel 1 antibody, Tpcn1 antibody, TPC1 antibody, TPCN1 antibody, tpcn1 antibody

Background: TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane.Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]).[supplied by OMIM].
Alias Symbols: FLJ20612, KIAA1169, TPC1
Protein Size: 816

Molecular Weight: 94 kDa

Gene ID: 53373

NCBI Accession: NM_017901, NP_060371

UniProt: Q9ULQ1