TNFAIP1 antibody (C-Term)

Catalog No. ABIN2776237

Product Details anti-TNFAIP1 Antibody

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LNVLLYETPR VPDNSLLEAT SRSRSQASPS EDEDTFELRD RVRRIHVKRY

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Tnfaip1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of RAT Tnfaip1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TNFAIP1

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Alternative Name: Tnfaip1 (TNFAIP1 Products)

Synonyms: zgc:55302 antibody, wu:fi06b02 antibody, TNFAIP1 antibody, B12 antibody, B61 antibody, BTBD34 antibody, EDP1 antibody, hBACURD2 antibody, Edp-1 antibody, Edp1 antibody, Tnfip1 antibody, tumor necrosis factor, alpha-induced protein 1 (endothelial) antibody, TNF alpha induced protein 1 antibody, TNF alpha induced protein 1 L homeolog antibody, tnfaip1 antibody, TNFAIP1 antibody, Tnfaip1 antibody, tnfaip1.L antibody

Background: Tnfaip1 is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis.
Alias Symbols: Edp1
Protein Interaction Partner: Pcna,
Protein Size: 316

Molecular Weight: 34 kDa

Gene ID: 287543

NCBI Accession: NM_182950, NP_891995

UniProt: Q7TNY1