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TRPV4 antibody (N-Term)
TRPV4
Reactivity: Human, Mouse, Rat, Cow, Pig, Dog
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TRPV4 Antibody
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Target
See all TRPV4 Antibodies
TRPV4
(Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
Binding Specificity
All epitopes for TRPV4 antibodies
N-Term
Reactivity
All reactivities for TRPV4 antibodies
Human, Mouse, Rat, Cow, Pig, Dog
Host
All hosts for TRPV4 antibodies
Rabbit
Clonality
All clonalities for TRPV4 antibodies
Polyclonal
Conjugate
All conjugates for TRPV4 antibodies
This TRPV4 antibody is un-conjugated
Application
All applications for TRPV4 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
AGPGEVAELP GDESGTPGGE AFPLSSLANL FEGEDGSLSP SPADASRPAG
Predicted Reactivity
Cow: 85%, Dog: 92%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 85%
Characteristics
This is a rabbit polyclonal antibody against TRPV4. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human TRPV4
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Discover our top product TRPV4 Primary Antibody
Alternatives
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anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Middle Region) antibody
TRPV4
Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Guinea Pig
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Internal Region) antibody
TRPV4
Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Hamster, Horse
WB, IHC, IF, IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (AA 853-871), (C-Term), (Intracellular) antibody
TRPV4
Reactivity: Human, Mouse, Rat
WB, IHC, FACS, IF, ICC, IP
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for TRPV4
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Target
TRPV4
(Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
Alternative Name
TRPV4 (TRPV4 Products )
Synonyms
wu:fp52e02 antibody, CMT2C antibody, HMSN2C antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, TRP12 antibody, VRL2 antibody, VROAC antibody, 0610033B08Rik antibody, Trp12 antibody, VR-OAC antibody, VRL-2 antibody, Otrpc4 antibody, Vroac antibody, transient receptor potential cation channel, subfamily V, member 4 antibody, transient receptor potential cation channel subfamily V member 4 antibody, trpv4 antibody, TRPV4 antibody, Trpv4 antibody
Background
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. Alias Symbols: SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1 Protein Size: 552
Molecular Weight
60 kDa
Gene ID
59341
NCBI Accession
NM_001177428 , NP_001170899
UniProt
Q9HBA0
Pathways
Hormone Transport , Cell-Cell Junction Organization
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