KCNH6 antibody (Middle Region)

Catalog No. ABIN2776258

Product Details anti-KCNH6 Antibody

Target: KCNH6 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6))

Binding Specificity: Middle Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNH6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRMPHLAVAT DKTLAPSSEQ EQPEGLWPPL ASPLHPLEVQ GLICGPCFSS

Predicted Reactivity: Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against KCNH6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCNH6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 905 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNH6

Target: KCNH6 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6))

Alternative Name: KCNH6 (KCNH6 Products)

Synonyms: KCNH2 antibody, erg antibody, ERG-2 antibody, ERG2 antibody, HERG2 antibody, Kv11.2 antibody, hERG-2 antibody, m-erg2 antibody, Erg2 antibody, potassium voltage-gated channel subfamily H member 6 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 6 antibody, KCNH6 antibody, Kcnh6 antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH6 encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Alias Symbols: ERG2, HERG2, Kv11.2
Protein Size: 905

Molecular Weight: 100 kDa

Gene ID: 81033

NCBI Accession: NM_173092, NP_775115