KCNK10 antibody (N-Term)

Catalog No. ABIN2776275

Product Details anti-KCNK10 Antibody

Target: KCNK10 (Potassium Channel, Subfamily K, Member 10 (KCNK10))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VVAIFVVVVV YLVTGGLVFR ALEQPFESSQ KNTIALEKAE FLRDHVCVSP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against KCNK10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNK10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 538 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNK10

Target: KCNK10 (Potassium Channel, Subfamily K, Member 10 (KCNK10))

Alternative Name: KCNK10 (KCNK10 Products)

Synonyms: KCNK10 antibody, K2p10.1 antibody, TREK-2 antibody, TREK2 antibody, 1700024D23Rik antibody, 3010005K24Rik antibody, Trek2 antibody, k2p10.1 antibody, trek-2 antibody, trek2 antibody, potassium two pore domain channel subfamily K member 10 antibody, potassium channel, subfamily K, member 10 antibody, potassium channel, two pore domain subfamily K, member 10 L homeolog antibody, KCNK10 antibody, Kcnk10 antibody, kcnk10.L antibody

Background: KCNK10 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
Alias Symbols: TREK2, TREK-2, K2p10.1
Protein Interaction Partner: PPP1CA, UBC,
Protein Size: 538

Molecular Weight: 59 kDa

Gene ID: 54207

NCBI Accession: NM_021161, NP_066984

UniProt: P57789