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KCNMB3 antibody (Middle Region)

KCNMB3 Reactivity: Human, Rat, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776296
  • Target See all KCNMB3 Antibodies
    KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
    Binding Specificity
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 18
    • 3
    • 1
    • 1
    Human, Rat, Dog
    Host
    • 15
    • 5
    Rabbit
    Clonality
    • 16
    • 4
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNMB3 antibody is un-conjugated
    Application
    • 9
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SLTLLGGALI VGMVRLTQHL SLLCEKYSTV VRDEVGGKVP YIEQHQFKLC
    Predicted Reactivity
    Dog: 91%, Human: 100%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against KCNMB3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human KCNMB3
    Top Product
    Discover our top product KCNMB3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 277 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
    Alternative Name
    KCNMB3 (KCNMB3 Products)
    Synonyms
    KCNMB3 antibody, BKBETA3 antibody, HBETA3 antibody, KCNMB2 antibody, KCNMBL antibody, SLOBETA3 antibody, EG435726 antibody, Gm5707 antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 3 antibody, potassium channel subfamily M regulatory beta subunit 3 S homeolog antibody, potassium large conductance calcium-activated channel, subfamily M beta member 3 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 3 antibody, KCNMB3 antibody, kcnmb3.S antibody, Kcnmb3 antibody
    Background
    KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for KCNMB3.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.
    Alias Symbols: KCNMB2, KCNMBL, HBETA3, BKBETA3, SLOBETA3
    Protein Size: 277
    Molecular Weight
    31 kDa
    Gene ID
    27094
    NCBI Accession
    NM_171828, NP_741979
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