GABRG2 antibody (C-Term)

Catalog No. ABIN2776351

Product Details anti-GABRG2 Antibody

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AMDLFVSVCF IFVFSALVEY GTLHYFVSNR KPSKDKDKKK KNPAPTIDIR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GABRG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABRG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRG2

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Alternative Name: GABRG2 (GABRG2 Products)

Synonyms: cae2 antibody, eca2 antibody, gabrg1 antibody, gefsp3 antibody, si:ch211-145n14.1 antibody, CAE2 antibody, ECA2 antibody, GEFSP3 antibody, GABAA-R antibody, Gabrg-2 antibody, gamma2 antibody, gamma-aminobutyric acid type A receptor gamma2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, gamma 2 antibody, gamma-aminobutyric acid type A receptor gamma 2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 antibody, GABRG2 antibody, gabrg2 antibody, Gabrg2 antibody

Background: Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. GABRG2 is the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. This gene encodes the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Alias Symbols: CAE2, ECA2, GEFSP3
Protein Interaction Partner: ZDHHC3, GABARAP, PRKCB, PRKCA, GABRG2, DRD5, PPP3CA,
Protein Size: 327

Molecular Weight: 36 kDa

Gene ID: 2566

NCBI Accession: NM_198903, NP_944493

UniProt: P18507