Serotonin Receptor 3A antibody (Middle Region)

Catalog No. ABIN2776369

Product Details anti-Serotonin Receptor 3A Antibody

Target: Serotonin Receptor 3A (HTR3A)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 3A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PATAIGTPLI GVYFVVCMAL LVISLAETIF IVQLVHKQDL QRPVPDWLRH

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Htr3a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Serotonin Receptor 3A

Target: Serotonin Receptor 3A (HTR3A)

Alternative Name: Htr3a (HTR3A Products)

Synonyms: MGC52789 antibody, HTR3A antibody, 5-HT3 antibody, 5HT3R antibody, HTR3 antibody, 5-HT-3 antibody, 5-HT3A antibody, 5-HT3R antibody, 5HT3 antibody, Htr3 antibody, 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic L homeolog antibody, 5-hydroxytryptamine receptor 3A antibody, 5-hydroxytryptamine (serotonin) receptor 3A antibody, htr3a.L antibody, HTR3A antibody, Htr3a antibody

Background: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Alias Symbols: 5-HT3, 5-HT3A, 5HT3, Htr3
Protein Size: 483

Molecular Weight: 55 kDa

Gene ID: 79246

NCBI Accession: NM_024394, NP_077370

UniProt: P35563

Pathways: Synaptic Membrane