PTBP2 antibody (N-Term)

Catalog No. ABIN2776545

Product Details anti-PTBP2 Antibody

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSSMVVTAN GNDSKKFKGE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PTBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 356 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PTBP2 antibody (ABIN2776545)

Tateiwa, Gotoh, Ichikawa, Kikuchi, Yoshimura: "Molecular cloning and characterization of human PTB-like protein: a possible retinal autoantigen of cancer-associated retinopathy." in: Journal of neuroimmunology, Vol. 120, Issue 1-2, pp. 161-9, (2001) (PubMed).

Target Details for PTBP2

Target: PTBP2 (Polypyrimidine Tract Binding Protein 2 (PTBP2))

Alternative Name: PTBP2 (PTBP2 Products)

Background: PTBP2 binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.
Alias Symbols: PTB, nPTB, PTBLP, brPTB, nPTB5, nPTB6, nPTB7, nPTB8
Protein Interaction Partner: PTBP2, RBM10, EIF5A2, PUF60, KHDRBS1, KHDRBS3, TOM1, MATR3, QKI, UBC, SNRPA, RBM4, HNRNPD, HNRNPC, HNRNPAB, ELAVL1, UBE2E2, PCBP3, SUMO2, CALCOCO2, KHSRP, FUS,
Protein Size: 356

Molecular Weight: 40 kDa

Gene ID: 58155

NCBI Accession: NM_021190

Pathways: Ribonucleoprotein Complex Subunit Organization, SARS-CoV-2 Protein Interactome