GPBAR1 antibody (C-Term)

Catalog No. ABIN2776714

Product Details anti-GPBAR1 Antibody

Target: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPBAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LDALTGFVVA PLFTYLVIGT LFIAAGLVAL FKIRSNLQKD GTKTDKLERL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GPCR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human FZD4

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPBAR1

Target: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Alternative Name: GPCR (GPBAR1 Products)

Synonyms: BG37 antibody, GPCR19 antibody, GPR131 antibody, M-BAR antibody, TGR5 antibody, Tgr5 antibody, MGC84403 antibody, GPBAR1 antibody, Gpbar1 antibody, GPCR antibody, G protein-coupled bile acid receptor 1 antibody, G protein-coupled bile acid receptor 1 S homeolog antibody, GPBAR1 antibody, Gpbar1 antibody, gpbar1.S antibody

Background: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Alias Symbols: Fz4, EVR1, FEVR, Fz-4, FzE4, GPCR, hFz4, CD344, FZD4S
Protein Size: 433

Molecular Weight: 47 kDa

Gene ID: 8322

NCBI Accession: NM_012193, NP_036325

UniProt: Q9ULV1

Pathways: WNT Signaling, Hormone Transport, Sensory Perception of Sound