WNT16 antibody (Wingless-Type MMTV Integration Site Family, Member 16) (Middle Region)

Details for Product anti-WNT16 Antibody No. ABIN2776716, Supplier: Log in to see
Antigen
  • zgc:77293
  • E130309I19Rik
  • wingless-type MMTV integration site family, member 16
  • wingless-related MMTV integration site 16
  • LOC100218349
  • LOC100353090
  • WNT16
  • wnt16
  • Wnt16
Alternatives
anti-Human WNT16 antibody for Immunofluorescence (fixed cells)
Epitope
Middle Region
13
12
8
8
3
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
60
19
19
6
4
2
2
2
2
1
1
Host
Rabbit
59
1
Clonality
Polyclonal
Conjugate
This WNT16 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
35
21
19
14
13
1
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human WNT16
Blocking Peptide Blocking peptide for this product available: ABIN986211
Sequence KTKRKMRRRE KDQRKIPIHK DDLLYVNKSP NYCVEDKKLG IPGTQGRECN
Predicted Reactivity Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against WNT16. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name WNT16 (WNT16 Antibody Abstract)
Background WNT proteins are secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT16 contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen.
Alias Symbols: -
Protein Interaction Partner: BCL6,
Protein Size: 355
Molecular Weight 40 kDa
Gene ID 51384
NCBI Accession NM_016087, NP_057171
UniProt Q9UBV4
Pathways WNT Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 355 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-WNT16 antibody (Wingless-Type MMTV Integration Site Family, Member 16) (Middle Region) (ABIN2776716) anti-Wingless-Type MMTV Integration Site Family, Member 16 (WNT16) (Middle Region) antibody
Background publications Casagrande, te Kronnie, Basso: "The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line." in: Haematologica, Vol. 91, Issue 6, pp. 765-71, 2006 (PubMed).