WDR5 antibody (C-Term)

Catalog No. ABIN2776739

Product Details anti-WDR5 Antibody

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NFSVTGGKWI VSGSEDNLVY IWNLQTKEIV QKLQGHTDVV ISTACHPTEN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Wdr5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: Wdr5 (WDR5 Products)

Synonyms: BIG-3 antibody, SWD3 antibody, 2410008O07Rik antibody, AA408785 antibody, AA960360 antibody, Big antibody, Big-3 antibody, zgc:56591 antibody, zgc:76895 antibody, wu:fk47f04 antibody, wdr5-a antibody, MGC80538 antibody, wdr5-b antibody, MGC81485 antibody, big-3 antibody, swd3 antibody, xwdr5 antibody, WDR5B antibody, WD repeat domain 5 antibody, WD repeat domain 5 L homeolog antibody, WD repeat domain 5 S homeolog antibody, WDR5 antibody, Wdr5 antibody, wdr5 antibody, wdr5.L antibody, wdr5.S antibody

Background: Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation.
Alias Symbols: 2410008O07Rik, AA408785, AA960360, Big, Big-3
Protein Interaction Partner: L3mbtl2, Phf20, Rbbp5, Csrp2bp, Mbip, Kat2a, Rnf2, Pou5f1, Runx1, Ctcf, Nfe2, Kmt2d, Kdm2b, Sall4, Tfcp2l1, Esrrb, Nr0b1,
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 140858

NCBI Accession: NM_080848, NP_543124

UniProt: P61965