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DPYS antibody (Middle Region)

DPYS Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776833
  • Target See all DPYS Antibodies
    DPYS (Dihydropyrimidinase (DPYS))
    Binding Specificity
    • 15
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 45
    • 14
    • 12
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse
    Host
    • 45
    • 2
    Rabbit
    Clonality
    • 46
    • 1
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DPYS antibody is un-conjugated
    Application
    • 38
    • 21
    • 17
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    LRPDPSTPDF LMNLLANDDL TTTGTDNCTF NTCQKALGKD DFTKIPNGVN
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against DPYS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DPYS
    Top Product
    Discover our top product DPYS Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 519 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Thomas, Chen, Lin, Tomlinson, Lam, Liu, Yeung, Chan, Wong: "Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients." in: Cerebrovascular diseases (Basel, Switzerland), Vol. 25, Issue 3, pp. 261-7, (2008) (PubMed).

  • Target
    DPYS (Dihydropyrimidinase (DPYS))
    Alternative Name
    DPYS (DPYS Products)
    Synonyms
    DHP antibody, DHPase antibody, 1200017I10Rik antibody, 1300004I01Rik antibody, dhp antibody, dihydropyrimidinase antibody, dihydropyrimidinase L homeolog antibody, DPYS antibody, Dpys antibody, Jann_1488 antibody, hydA antibody, h16_A3075 antibody, Veis_0725 antibody, AZC_1966 antibody, M446_2543 antibody, RSKD131_3628 antibody, Vapar_5601 antibody, Rleg_5687 antibody, LOC9307588 antibody, EIO_3239 antibody, blr3333 antibody, BAV0676 antibody, hyuA antibody, CtCNB1_2936 antibody, dpyS antibody, Pat9b_1914 antibody, dpys antibody, dpys.L antibody
    Background
    Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
    Alias Symbols: DHP, DHPase
    Protein Interaction Partner: DPYSL5,
    Protein Size: 519
    Molecular Weight
    56 kDa
    Gene ID
    1807
    NCBI Accession
    NM_001385, NP_001376
    UniProt
    Q14117
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